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1.
Rev. argent. dermatol ; 89(4): 220-224, oct.-dic. 2008. ilus
Article in Spanish | LILACS | ID: lil-634374

ABSTRACT

Acute generalized exanthematous pustulosis (AGEP) is a rare skin eruption most commonly caused by medications. It is characterized by an acute eruption of sterile pustules and it is accompanied by an episode of fever, which regresses a few days after discontinuation of the drug that caused the condition. We report a case 23 year-old woman without history of psoriasis, that consults for fever and an acute generalized pustular eruption after amoxicillin, with clavulanic acid administration in a mononucleosis infection context, which resolved spontaneously. The microbiologic culture was negative for pathogenic germens.


La pustulosis exantemática aguda generalizada (PEAG) es una rara afección de hipersensibilidad, inducida principalmente por drogas y se manifiesta por una erupción aguda de pústulas estériles, acompañada de fiebre, que regresa en pocos días luego de discontinuar el fármaco causante. Se comunica el caso de una paciente de 23 años de edad, sin antecedentes de psoriasis que consulta por fiebre y una erupción pustulosa generalizada, asociada a la ingesta previa de amoxicilina y ácido clavulánico en el contexto de una mononucleosis infecciosa, con resolución espontánea del cuadro. El cultivo microbiológico no objetivó gérmenes patógenos.


Subject(s)
Humans , Female , Adult , Acute Generalized Exanthematous Pustulosis/pathology , Acute Generalized Exanthematous Pustulosis/diagnosis , Acute Generalized Exanthematous Pustulosis/physiopathology , Diagnosis, Differential , Herpesvirus 4, Human/pathogenicity
2.
Rev. argent. dermatol ; 89(3): 188-192, jul.-sep. 2008. ilus, tab
Article in Spanish | LILACS | ID: lil-634368

ABSTRACT

El Síndrome de Stevens Johnson (SSJ), el Síndrome de Superposición (SSJ/ NET) y la Necrólisis Epidérmica Tóxica (NET) son formas clínicas cutáneo-mucosas graves, desencadenadas por fármacos y muy frecuentemente por anticonvulsivantes. Comunicamos el caso de una paciente medicada por su epilepsia, quién presentó un cuadro incipiente de SSJ empeorando rápidamente hasta derivar en la NET. A pesar de la gravedad, la paciente respondió satisfactoriamente a altas dosis de corticoides sistémicos desde el comienzo y por las medidas de soporte del equipo médico multidisciplinario del hospital.


The Stevens Johnson Syndrome, the Overlape Syndrome (SSJ / NET), and the Toxic Epidermal Necrolysis are clinical cutaneous mucouse forms due to drugs administration and most frequently due caused by antiepileptic. We communicate the case of a patient treated with lamotrigina for epilepsy, who presented an incipient case of Stevens Johnson Syndrome, worsened rapidly causing a Toxic Epidermal Necrolysis. Nevertheless, the patient gained a satisfactory answer due to high doses of corticoids, which were given from the beginning as well as the measures and the support of the whole medical team of the hospital.


Subject(s)
Humans , Female , Adult , Anticonvulsants/poisoning , Anticonvulsants/adverse effects , Drug-Related Side Effects and Adverse Reactions/complications , Stevens-Johnson Syndrome/diagnosis , Stevens-Johnson Syndrome/drug therapy
3.
Rev. argent. dermatol ; 89(2): 66-72, abr.-jun. 2008. ilus
Article in Spanish | LILACS | ID: lil-634357

ABSTRACT

Se reporta el caso de un paciente masculino de 23 años de edad, que se presenta con una úlcera de región latero cervical, única, sin compromiso del estado general. Se solicita estudio histopatológico de la lesión e inmunomarcación, con diagnóstico de Linfoma no Hodgkin B de células grandes cutáneos primarios. Se realiza una revisión sobre los Linfomas no Hodgkin B de células grandes cutáneos primarios, siendo anecdótica la presentación en pacientes jóvenes.


We report a case of a 23 year old male with a lateral cervical ulcer, without general involvement. Histophatological study and immunomarcation were positive to non Hodgkin Difuse Primary Cutaneous Large B-Cell Lymphoma. A revision was made about Primary Cutaneous B-Cell Lymphomas, being unusual this presentation in young people.


Subject(s)
Humans , Male , Adult , Lymphoma, Large B-Cell, Diffuse/pathology , Lymphoma, Large B-Cell, Diffuse/epidemiology , Lymphoma, Large B-Cell, Diffuse/therapy , Signs and Symptoms , Skin Ulcer/diagnosis
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